๐Ÿงฌ AI-Powered Lab Intelligence

Your lab data,
one question away

Hillkrest builds custom AI agents that connect directly to your databases and live inside your team's Slack. Ask questions in plain English โ€” get answers from your actual data in seconds.

# data-assistant
๐Ÿ‘ฉโ€๐Ÿ”ฌ
Sarah Chen
@Hillkrest what's the IC50 for compound HK-447 against OV90?
H
Hillkrest
HK-447 against OV90 (CTG SA assay, run 2026-03-28):
โ€ข IC50: 0.847 ยตM (Rยฒ = 0.994)
โ€ข Hill slope: -1.23
โ€ข Max inhibition: 94.2%

This ranks #3 out of 13 compounds tested in that panel. Want me to export the full dose-response curve as CSV?
๐Ÿ‘ฉโ€๐Ÿ”ฌ
Sarah Chen
Yes, and compare it to the JEG3 results too
H
Hillkrest
๐Ÿ“Ž HK-447_OV90_vs_JEG3_comparison.csv attached.
Quick summary: HK-447 is 3.2ร— more potent against OV90 (IC50 0.847 ยตM) vs JEG3 (2.71 ยตM). Consistent across both runs.
<5s
Query Response
10+
Users Supported
24/7
Always Available
0
Data Leaves Your Network

What It Does

A conversational AI agent that sits on top of your lab data and makes your entire team faster.

๐Ÿ’ฌ

Natural Language Queries

Ask questions in plain English. "What's the most potent compound against OV90?" โ€” no SQL, no clicking through dashboards, no waiting for a bioinformatician.

๐Ÿ”Œ

Direct Database Connection

Connects to your existing data โ€” whether that's a structured database, exported Prism files, or Excel spreadsheets. Your data stays where it is.

๐Ÿ“Š

Automated Curve Fitting

4-parameter logistic (4PL) dose-response fitting with IC50 calculation, Hill slope, and Rยฒ quality metrics โ€” computed automatically on ingestion.

๐Ÿ“

File Upload Ingestion

Drop a .prism or .xlsx file into the Slack DM. The agent auto-parses it, runs curve fits, ingests to the database, and confirms โ€” in under 30 seconds.

๐Ÿ“ค

CSV & Report Export

Any query result can be exported as a formatted CSV file, delivered right in Slack. Ready for presentations, regulatory submissions, or further analysis.

๐Ÿง 

Conversational Memory

Per-user conversation history means the agent remembers context. Follow-up questions work naturally โ€” "now compare that to JEG3" just works.

How It Works

From raw assay data to instant answers in four steps.

1

Data Ingestion

Upload GraphPad Prism files, Excel exports, or connect directly to your ELN. The agent parses, normalizes, and stores everything in a structured database.

2

Automated Analysis

Dose-response curves are fit automatically. IC50s, Hill slopes, and quality metrics computed for every compound ร— cell line combination.

3

Slack Integration

The AI agent lives in your Slack workspace. @mention it in channels or DM it directly. Your team gets answers where they already work.

4

Instant Answers

Ask anything about your data in plain English. Cross-experiment comparisons, potency rankings, historical trends โ€” all in seconds.

Purpose-Built Architecture

Designed for biotech teams that need power without complexity.

On-Premise, Under Your Control

The entire system runs on a dedicated machine at your facility. Your data never leaves your network โ€” the only external calls are to the AI model API (with zero-retention options available).

No cloud dependencies. No shared infrastructure. No third-party data access. Just your data, your machine, your team.

  • Dedicated hardware at your site (Lenovo ThinkStation)
  • SQLite database โ€” simple, fast, zero-config
  • Claude AI for natural language understanding
  • Slack Socket Mode โ€” no inbound ports needed
  • Systemd managed โ€” auto-restart, structured logging
  • Encrypted disk (LUKS), firewall (UFW), intrusion detection
โ”Œโ”€โ”€โ”€ Your Facility โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”
โ”‚
โ”‚  [Slack Workspace]
โ”‚      โ†• Socket Mode (outbound only)
โ”‚  [Hillkrest Agent]
โ”‚      โ†• Local queries
โ”‚  [SQLite Database]
โ”‚      โ†• Auto-parse on upload
โ”‚  [Prism / Excel Files]
โ”‚
โ””โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”˜

       โ†• HTTPS (encrypted, outbound only)

  [Claude API] โ€” zero retention available

Security First

Your research data is your competitive advantage. We treat it that way.

On-Premise

Data Never Leaves

Your database lives on hardware you physically control. No cloud storage, no shared servers, no multi-tenant risk. Pull the ethernet cable and everything still works locally.

Encrypted

Full Disk Encryption

LUKS encrypted storage means even physical theft of the machine yields nothing. Combined with UFW firewall and Fail2ban intrusion detection.

Zero Retention

AI with No Memory

Anthropic's enterprise API terms ensure your queries are never stored or used for model training. Your compound names and assay data don't become training data.

Access Control

Remote Access Options

Choose your security posture: Tailscale VPN (encrypted mesh), Cloudflare Zero Trust (identity-aware), or fully air-gapped (LAN only). You decide.

Built for Biotech Teams

Whether you're 5 people or 50, if you have assay data, we can make it talk.

Discovery

Drug Discovery Labs

Compare compound potency across cell lines instantly. Rank your hits, track SAR trends, and identify leads without digging through spreadsheets. Your medicinal chemists get answers in seconds.

Operations

Lab Operations & QC

Track assay performance over time. Flag drift in control values. Ensure reproducibility across runs. The agent watches your data quality so you don't have to.

Leadership

Program Reviews

"Give me the top 5 compounds by selectivity ratio across all our oncology panels." Get the answer in Slack instead of waiting for someone to build a slide.

Ready to unlock your lab data?

We'll scope a custom agent for your team, connect it to your data, and have it running in Slack within weeks โ€” not months.

Let's Talk โ†’